New Delhi Metallo-β-Lactamase-1–Producing Klebsiella pneumoniae, Florida, USA1

Technical Appendix Figure. Major structural features of plasmid pK351 indicated with bold type, compared with closely related blaNDM-1-positive plasmid pNDM-Ec1GN574 (KJ812998), pKOX_NDM1 KP826710.1). Light gray shades indicate shared regions with a high degree of homology. ORFs are portrayed by arrows and colored according to their putative functions. Dark-blue arrows indicate replication associated genes. Genes associated with plasmid conjugal transfer are indicated by green arrows, and genes involved in plasmid stability are indicated by brown arrows. Red and yellow arrows indicate antimicrobial resistance genes and mobile elements genes, respectively. Grey arrows indicate genes for hypothetical proteins as well as proteins of unknown function.